英文名称ANO1/TMEM16A
中文名称跨膜蛋白16A/钙激活氯离子通道单克隆抗体
别    名ANO 1;ANO1_HUMAN; Anoctamin 1; Anoctamin 1 calcium activated chloride channel; Anoctamin-1; Anoctamin1; Discovered on gastrointestinal stromal tumors protein 1; DOG 1; FLJ10261; Membrane protein; Oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV 2; ORAOV2; TAOS 2; TAOS2; TMEM 16A; TMEM16A; Transmembrane protein 16A (eight membrane spanning domains); Transmembrane protein 16A; Tumor amplified and overexpressed sequence 2; Tumor-amplified and overexpressed sequence 2.  
研究领域肿瘤  细胞生物  免疫学  
抗体来源Mouse
克隆类型Monoclonal
交叉反应Human, Rat, 
产品应用IHC-P=1:400-800 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量114kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ANO1/TMEM16A 
亚    型IgG1
纯化方法affinity purified by Protein G
缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍TMEM16A (Transmembrane protein 16A) is an eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products and is amplified in various cancers. It acts as a calcium-activated chloride channel and is required for normal tracheal development.

Function:
Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasm.

Tissue Specificity:
Broadly expressed with higher levels in liver and skeletal muscle.

Similarity:
Belongs to the anoctamin family.

SWISS:
Q5XXA6

Gene ID:
55107